| Datum | Heimteam | - | Gastteam | Tipp | S | 102 | </> | Erg | Erg |
| 40.Runde 21/22 | |||||||||
| 13.05.22 | Real Sociedad B | - | UD Almeria | 0:1 | o | 2 | < | 0:1 | |
| 14.05.22 | Burgos CF | - | FC Cartagena | 1:0 | o | 1 | < | 1:0 | |
| 14.05.22 | CD Leganes | - | SD Eibar | 0:1 | + | 2 | < | 0:1 | |
| 14.05.22 | CD Lugo | - | CF Fuenlabrada | 2:1 | o | 1 | > | 2:1 | |
| 14.05.22 | Real Valladolid C | - | SD Ponferradina | 2:1 | o | 1 | > | 2:1 | |
| 14.05.22 | SD Amorebieta | - | SD Huesca | 1:1 | o | 0 | < | 1:1 | |
| 15.05.22 | CD Mirandés | - | UD Ibiza | 2:1 | o | 1 | > | 2:1 | |
| 15.05.22 | Sporting de Gijon | - | Girona FC | 0:2 | o | 2 | < | 0:2 | |
| 15.05.22 | CD Teneriffa | - | Malaga CF | 1:0 | o | 1 | < | 1:0 | |
| 15.05.22 | AD Alcorcón | - | UD Las Palmas | 0:2 | o | 2 | < | 0:2 | |
| 16.05.22 | Real Oviedo | - | Real Saragossa | 1:0 | o | 1 | < | 1:0 | |
| - | |||||||||
| 39.Runde 21/22 | |||||||||
| 06.05.22 | UD Las Palmas | - | CD Mirandés | 2:1 | o | OK | <> | <> | 1:0 |
| 07.05.22 | CF Fuenlabrada | - | Real Sociedad B | 1:2 | o | OK | OK | OK | 1:2 |
| 07.05.22 | SD Huesca | - | Sporting de Gijon | 1:0 | o | <> | OK | <> | 1:1 |
| 07.05.22 | Malaga CF | - | Real Oviedo | 0:2 | o | <> | OK | <> | 0:0 |
| 07.05.22 | SD Ponferradina | - | Burgos CF | 2:1 | o | OK | OK | <> | 3:1 |
| 07.05.22 | UD Almeria | - | SD Amorebieta | 1:0 | o | OK | <> | <> | 3:0 |
| 08.05.22 | SD Eibar | - | Real Valladolid C | 1:0 | o | <> | OK | <> | 0:2 |
| 08.05.22 | UD Ibiza | - | CD Lugo | 1:1 | o | OK | OK | OK | 1:1 |
| 08.05.22 | Real Saragossa | - | AD Alcorcón | 1:0 | o | <> | <> | <> | 0:3 |
| 08.05.22 | FC Cartagena | - | CD Leganes | 2:1 | o | <> | <> | <> | 0:0 |
| 09.05.22 | Girona FC | - | CD Teneriffa | 1:0 | + | <> | OK | <> | 0:1 |
| - | |||||||||
| 38.Runde 21/22 | |||||||||
| 29.04.22 | UD Las Palmas | - | Malaga CF | 1:0 | o | OK | <> | <> | 2:1 |
| 30.04.22 | Burgos CF | - | UD Almeria | 1:0 | o | <> | OK | <> | 0:2 |
| 30.04.22 | SD Eibar | - | Real Saragossa | 1:0 | o | OK | OK | <> | 2:0 |
| 30.04.22 | Real Oviedo | - | CD Mirandés | 2:1 | + | OK | OK | <> | 3:0 |
| 01.05.22 | CD Lugo | - | CD Teneriffa | 1:1 | o | <> | OK | <> | 0:2 |
| 01.05.22 | SD Ponferradina | - | FC Cartagena | 2:1 | o | OK | OK | <> | 4:2 |
| 01.05.22 | Sporting de Gijon | - | UD Ibiza | 0:1 | o | OK | OK | OK | 0:1 |
| 01.05.22 | AD Alcorcón | - | Girona FC | 0:2 | o | OK | OK | <> | 0:1 |
| 01.05.22 | SD Amorebieta | - | CF Fuenlabrada | 2:1 | o | OK | OK | OK | 2:1 |
| 02.05.22 | CD Leganes | - | SD Huesca | 1:1 | o | <> | <> | <> | 2:1 |
| 02.05.22 | Real Valladolid C | - | Real Sociedad B | 1:0 | o | <> | <> | <> | 1:2 |
| - | |||||||||
| 37.Runde 21/22 | |||||||||
| 22.04.22 | CD Teneriffa | - | SD Huesca | 1:0 | o | <> | OK | <> | 0:0 |
| 23.04.22 | CF Fuenlabrada | - | SD Ponferradina | 1:2 | o | OK | OK | <> | 2:3 |
| 23.04.22 | Malaga CF | - | SD Eibar | 0:2 | o | OK | <> | <> | 1:3 |
| 23.04.22 | Real Sociedad B | - | SD Amorebieta | 0:1 | o | <> | <> | <> | 2:1 |
| 23.04.22 | FC Cartagena | - | Girona FC | 1:2 | + | <> | OK | <> | 3:0 |
| 24.04.22 | UD Ibiza | - | UD Las Palmas | 1:0 | o | <> | OK | <> | 1:1 |
| 24.04.22 | CD Lugo | - | CD Leganes | 1:0 | o | <> | OK | <> | 0:0 |
| 24.04.22 | CD Mirandés | - | Real Valladolid C | 2:1 | o | <> | <> | <> | 0:1 |
| 24.04.22 | Real Saragossa | - | Burgos CF | 1:0 | o | <> | OK | <> | 0:0 |
| 24.04.22 | AD Alcorcón | - | Real Oviedo | 1:1 | o | <> | <> | <> | 1:2 |
| 25.04.22 | UD Almeria | - | Sporting de Gijon | 1:0 | o | OK | OK | OK | 1:0 |
| - | |||||||||
| 36.Runde 21/22 | |||||||||
| 15.04.22 | SD Eibar | - | UD Las Palmas | 1:0 | o | <> | <> | <> | 2:2 |
| 15.04.22 | SD Amorebieta | - | CD Mirandés | 1:1 | o | <> | OK | <> | 1:0 |
| 16.04.22 | CD Leganes | - | Malaga CF | 1:0 | + | <> | <> | <> | 0:3 |
| 16.04.22 | Sporting de Gijon | - | Real Oviedo | 0:2 | + | OK | OK | <> | 0:1 |
| 16.04.22 | Real Valladolid C | - | UD Almeria | 1:0 | o | <> | <> | <> | 2:2 |
| 16.04.22 | FC Cartagena | - | AD Alcorcón | 2:1 | o | OK | OK | <> | 3:1 |
| 17.04.22 | SD Huesca | - | Real Saragossa | 1:0 | o | <> | OK | <> | 1:1 |
| 17.04.22 | SD Ponferradina | - | CD Lugo | 1:1 | o | <> | <> | <> | 3:1 |
| 17.04.22 | CD Teneriffa | - | CF Fuenlabrada | 1:0 | o | OK | <> | <> | 3:1 |
| 17.04.22 | Burgos CF | - | UD Ibiza | 1:0 | o | OK | <> | <> | 2:1 |
| 18.04.22 | Girona FC | - | Real Sociedad B | 1:0 | o | OK | OK | <> | 2:0 |
| - | |||||||||
| 35.Runde 21/22 | |||||||||
| 08.04.22 | CD Lugo | - | FC Cartagena | 1:0 | o | OK | OK | OK | 1:0 |
| 09.04.22 | AD Alcorcón | - | Sporting de Gijon | 1:1 | o | OK | OK | OK | 1:1 |
| 09.04.22 | UD Las Palmas | - | SD Amorebieta | 1:1 | o | <> | OK | <> | 1:0 |
| 09.04.22 | Malaga CF | - | Real Valladolid C | 1:2 | o | <> | OK | <> | 2:2 |
| 09.04.22 | Real Sociedad B | - | CD Teneriffa | 0:1 | o | OK | <> | <> | 1:2 |
| 10.04.22 | Real Saragossa | - | Girona FC | 0:1 | + | <> | OK | <> | 1:0 |
| 10.04.22 | CF Fuenlabrada | - | SD Huesca | 1:1 | o | <> | <> | <> | 2:3 |
| 10.04.22 | UD Ibiza | - | SD Eibar | 0:2 | o | <> | OK | <> | 2:0 |
| 10.04.22 | CD Mirandés | - | Burgos CF | 1:0 | o | OK | <> | <> | 3:1 |
| 10.04.22 | Real Oviedo | - | CD Leganes | 1:0 | o | OK | OK | OK | 1:0 |
| 11.04.22 | UD Almeria | - | SD Ponferradina | 1:0 | o | OK | <> | <> | 3:0 |
| - | |||||||||
| 34.Runde 21/22 | |||||||||
| 01.04.22 | Girona FC | - | Malaga CF | 3:1 | o | OK | <> | <> | 1:0 |
| 02.04.22 | SD Amorebieta | - | UD Ibiza | 1:1 | o | <> | <> | <> | 3:1 |
| 02.04.22 | Real Sociedad B | - | AD Alcorcón | 1:0 | o | <> | <> | <> | 2:4 |
| 02.04.22 | CD Teneriffa | - | Real Saragossa | 1:0 | o | <> | OK | <> | 1:1 |
| 02.04.22 | Real Valladolid C | - | CD Lugo | 1:0 | o | OK | <> | <> | 4:1 |
| 03.04.22 | Burgos CF | - | Sporting de Gijon | 1:0 | o | <> | OK | <> | 0:0 |
| 03.04.22 | FC Cartagena | - | Real Oviedo | 1:0 | o | <> | <> | <> | 1:2 |
| 03.04.22 | SD Eibar | - | CD Mirandés | 3:1 | o | <> | <> | <> | 1:1 |
| 03.04.22 | SD Huesca | - | UD Almeria | 0:1 | o | <> | OK | <> | 1:1 |
| 03.04.22 | SD Ponferradina | - | UD Las Palmas | 1:1 | o | <> | <> | <> | 1:2 |
| 04.04.22 | CD Leganes | - | CF Fuenlabrada | 1:0 | o | OK | <> | <> | 3:2 |